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Thesis

Mechanism of acid influx in the carotid body type I cell

Abstract:

Type I cells of the carotid body play a major role in acid chemoreception. Extracellular acidosis causes membrane depolarisation, Ca2+ influx and neurosecretion in the type I cell. A previous study has shown that pHi in the type I cell is very sensitive to changes of pHo, and intracellular acidification is a key step in the signalling pathway for acid chemoreception. This thesis investigates the mechanism responsible for mediating acid influx during isocap...

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Institution:
University of Oxford
Department:
Life and Environmental Sciences Division

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Role:
Supervisor
Role:
Supervisor
Publication date:
2003
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Barcode:
603838258
URN:
uuid:683bdddf-e8a0-4abb-8d68-35b9188057e0
Local pid:
td:603838258
Language:
English
Subjects:

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