Thesis
Mechanism of acid influx in the carotid body type I cell
- Abstract:
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Type I cells of the carotid body play a major role in acid chemoreception. Extracellular acidosis causes membrane depolarisation, Ca2+ influx and neurosecretion in the type I cell. A previous study has shown that pHi in the type I cell is very sensitive to changes of pHo, and intracellular acidification is a key step in the signalling pathway for acid chemoreception. This thesis investigates the mechanism responsible for mediating acid influx during isocap...
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Authors
Contributors
+ Vaughan-Jones, R
Role:
Supervisor
+ Buckler, K
Role:
Supervisor
+ Buckler, K
Role:
Supervisor
+ Vaughan-Jones, R
Role:
Supervisor
Bibliographic Details
- Publication date:
- 2003
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Source identifiers:
-
603838258
Item Description
- Language:
- English
- Subjects:
- UUID:
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uuid:683bdddf-e8a0-4abb-8d68-35b9188057e0
- Local pid:
- td:603838258
- Deposit date:
- 2013-01-18
Terms of use
- Copyright holder:
- Tsai Ke-Li
- Copyright date:
- 2003
- Notes:
- The digital copy of this thesis has been made available thanks to the generosity of Dr Leonard Polonsky
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