Working paper
Re-purposing Ac/Ds transgenic system for CRISPR/dCas9 modulation of enhancers and non-coding RNAs in zebrafish
- Abstract:
-
Due to its genetic amenability coupled with recent advances in genome editing, the zebrafish serves as an excellent model to examine the function of both coding and non-coding elements. Recently, the non-coding genome has gained prominence due to its critical role in development and disease. Here, we have re-purposed the Ac/Ds maize transposition system to reliably screen and efficiently characterise zebrafish enhancers, with or without germline propagation. We further utilised the system to ...
Expand abstract
- Publication status:
- Not published
- Peer review status:
- Not peer reviewed
Actions
Authors
Bibliographic Details
- Series:
- bioRxiv
- Host title:
- bioRxiv
- Publication date:
- 2018-10-23
- Source identifiers:
-
942188
Item Description
Terms of use
- Copyright holder:
- Chong-Morrison et al
- Copyright date:
- 2018
- Notes:
- This is the pre-print version of the article
If you are the owner of this record, you can report an update to it here: Report update to this record