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Journal article

Disentangling the genetics of lean mass

Abstract:

Background:Lean body mass (LM) plays an important role in mobility and metabolic function. We previously identified five loci associated with LM adjusted for fat mass in kilograms. Such an adjustment may reduce the power to identify genetic signals having an association with both lean mass and fat mass. Objectives:To determine the impact of different fat mass adjustments on genetic architecture of LM and identify additional LM loci. Methods:We performed genome-wide association analyses for wh...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/ajcn/nqy272

Authors


More from this funder
Name:
Medical Research Council
Grant:
MC_UU_00007/10
More from this funder
Name:
NIA NIH HHS
Grant:
U24 AG051129
Publisher:
Oxford University Press
Journal:
American Journal of Clinical Nutrition More from this journal
Volume:
109
Issue:
2
Pages:
276-287
Publication date:
2019-02-05
Acceptance date:
2018-09-11
DOI:
EISSN:
1938-3207
ISSN:
0002-9165
Pmid:
30721968
Language:
English
Keywords:
Pubs id:
pubs:969098
UUID:
uuid:6821c6d2-1080-4533-ac13-8b590f5dc4b9
Local pid:
pubs:969098
Source identifiers:
969098
Deposit date:
2019-03-14

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