- Abstract:
-
Background:Lean body mass (LM) plays an important role in mobility and metabolic function. We previously identified five loci associated with LM adjusted for fat mass in kilograms. Such an adjustment may reduce the power to identify genetic signals having an association with both lean mass and fat mass. Objectives:To determine the impact of different fat mass adjustments on genetic architecture of LM and identify additional LM loci. Methods:We performed genome-wide association analyses for wh...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Department:
- Hebrew SeniorLife Institute for Aging Research and Harvard Medical School, Boston, MA.
- Publisher:
- Oxford University Press Publisher's website
- Journal:
- American Journal of Clinical Nutrition Journal website
- Volume:
- 109
- Issue:
- 2
- Pages:
- 276-287
- Publication date:
- 2019-02-05
- Acceptance date:
- 2018-09-11
- DOI:
- EISSN:
-
1938-3207
- ISSN:
-
0002-9165
- Pubs id:
-
pubs:969098
- URN:
-
uri:6821c6d2-1080-4533-ac13-8b590f5dc4b9
- UUID:
-
uuid:6821c6d2-1080-4533-ac13-8b590f5dc4b9
- Local pid:
- pubs:969098
- Language:
- English
- Keywords:
- Copyright date:
- 2019
Journal article
Disentangling the genetics of lean mass
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