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Molecular and cellular mechanisms of antidepressant action.

Abstract:

A long-standing theory is that brain monoamine signalling is critically involved in the mechanisms of antidepressant drug treatment. Theories on the nature of these mechanisms commenced with ideas developed in the 1960s that the drugs act simply by increasing monoamine availability in the synapse. However, this thinking has advanced remarkably in the last decade to concepts which position that antidepressant drug action on monoamine signalling is just the starting point for a complex sequence...

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Publisher copy:
10.1007/7854_2012_216

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Institution:
University of Oxford
Department:
Oxford, MSD, Pharmacology
Journal:
Current topics in behavioral neurosciences
Volume:
14
Pages:
309-325
Publication date:
2013
DOI:
EISSN:
1866-3389
ISSN:
1866-3370
URN:
uuid:68213a5d-bea8-4d75-82ec-5a2ff2ce648b
Source identifiers:
345688
Local pid:
pubs:345688

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