- Abstract:
-
The merged inverse-electron-demand hetero-Diels-Alder (ihDA)/retro-Diels-Alder (rDA) reaction sequence can be used to rapidly synthesise highly functionalised nitrogen heteroaromatics. The reaction offers many advantages: high atom economy, high levels of regioselectivity, it rarely requires a catalyst and, in some cases, can be performed in the absence of solvent. In this tutorial review we discuss the range of commonly used dienophiles and aza-dienes for this process whilst highlighting the...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1039/c2cs35316d
-
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- Journal:
- Chemical Society reviews
- Volume:
- 42
- Issue:
- 1
- Pages:
- 63-76
- Publication date:
- 2013-01-05
- DOI:
- EISSN:
-
1460-4744
- ISSN:
-
0306-0012
- URN:
-
uuid:6820fbbd-3063-4227-a39a-96e52e2a2bf2
- Source identifiers:
-
356185
- Local pid:
- pubs:356185
- Language:
- English
- Copyright date:
- 2013
Journal article
Tandem inverse-electron-demand hetero-/retro-Diels-Alder reactions for aromatic nitrogen heterocycle synthesis.
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