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From segment to somite: segmentation to epithelialization analyzed within quantitative frameworks.

Abstract:

One of the most visually striking patterns in the early developing embryo is somite segmentation. Somites form as repeated, periodic structures in pairs along nearly the entire caudal vertebrate axis. The morphological process involves short- and long-range signals that drive cell rearrangements and cell shaping to create discrete, epithelialized segments. Key to developing novel strategies to prevent somite birth defects that involve axial bone and skeletal muscle development is understandin...

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Publication status:
Published

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Publisher copy:
10.1002/dvdy.21199

Authors


Kulesa, PM More by this author
Schnell, S More by this author
Rudloff, S More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Mathematical Inst
Journal:
Developmental dynamics : an official publication of the American Association of Anatomists
Volume:
236
Issue:
6
Pages:
1392-1402
Publication date:
2007-06-05
DOI:
EISSN:
1097-0177
ISSN:
1058-8388
URN:
uuid:681fb2c0-c8a4-4dc4-ab01-c7be04a71e36
Source identifiers:
5844
Local pid:
pubs:5844

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