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Journal article

C-H activation: Complex peptides made simple.

Abstract:

Naturally occurring peptides exhibit an extraordinary range of properties and biological activities1. Nonribosomal peptides (NRPs) continue to represent an invaluable source of new small-molecule drugs2, having already provided antibiotics such as the β-lactam, glycopeptide and lipopeptide families3. Advances in the bioengineering of NRP synthases4 and the availability of non‑proteinogenic amino acids have expanded the compound pool available to researchers in recent years, but chemical synth...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/nchem.2701

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Publisher:
Nature Publishing Group
Journal:
Nature Chemistry More from this journal
Volume:
9
Issue:
1
Pages:
9-10
Publication date:
2017-01-01
DOI:
EISSN:
1755-4349
ISSN:
1755-4330
Pmid:
27995919
Language:
English
Keywords:
Pubs id:
pubs:736833
UUID:
uuid:681a7c0a-325b-4375-9e4e-7b8d9c36d306
Local pid:
pubs:736833
Source identifiers:
736833
Deposit date:
2017-10-26

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