Journal article icon

Journal article

2018 update to the HIV-TRePS system: the development of new computational models to predict HIV treatment outcomes, with or without a genotype, with enhanced usability for low-income settings

Abstract:
Objectives Optimizing antiretroviral drug combination on an individual basis can be challenging, particularly in settings with limited access to drugs and genotypic resistance testing. Here we describe our latest computational models to predict treatment responses, with or without a genotype, and compare their predictive accuracy with that of genotyping. Methods Random forest models were trained to predict the probability of virological response to a new the... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

Actions


Access Document


Files:
Publisher copy:
10.1093/jac/dky179

Authors


Expand authors...
National Institute of Allergy and Infectious Diseases More from this funder
Publisher:
Oxford University Press Publisher's website
Journal:
Journal of Antimicrobial Chemotherapy Journal website
Volume:
73
Issue:
8
Pages:
2186–2196
Publication date:
2018-06-08
Acceptance date:
2018-04-17
DOI:
EISSN:
1460-2091
ISSN:
0305-7453
Pubs id:
pubs:935990
URN:
uri:68178b60-e2bf-4435-830f-2c3343d187a8
UUID:
uuid:68178b60-e2bf-4435-830f-2c3343d187a8
Local pid:
pubs:935990

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP