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The highly ordered double-stranded RNA genome of bluetongue virus revealed by crystallography.

Abstract:

The concentration of double-stranded RNA within the bluetongue virus core renders the genome segments liquid crystalline. Powder diffraction rings confirm this local ordering with a 30 A separation between strands. Determination of the structure of the bluetongue virus core serotype 10 and comparison with that of serotype 1 reveals most of the genomic double-stranded RNA, packaged as well-ordered layers surrounding putative transcription complexes at the apices of the particle. The outer laye...

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Publication status:
Published

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Authors


Diprose, JM More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Structural Biology
Burroughs, JN More by this author
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Journal:
Cell
Volume:
97
Issue:
4
Pages:
481-490
Publication date:
1999-05-05
DOI:
EISSN:
1097-4172
ISSN:
0092-8674
URN:
uuid:680faffa-ad9b-488e-8f6f-65b19f6bd596
Source identifiers:
18611
Local pid:
pubs:18611

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