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RNA 3' end signals of the S.pombe ura4 gene comprise a site determining and efficiency element.

Abstract:

We have defined sequences in the 3' non-coding region of the Schizosaccharomyces pombe ura4 gene that are required for efficient mRNA 3' end formation. Three separate sequence elements have been identified. Two of these are site determining elements which specify alternative sites of polyadenylation [the major poly(A) site and a minor downstream poly(A) site]. The third sequence, located downstream of both poly(A) sites, functions as an efficiency element that enhances utilization of either p...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Journal:
EMBO journal
Volume:
13
Issue:
10
Pages:
2441-2451
Publication date:
1994-05-01
EISSN:
1460-2075
ISSN:
0261-4189
Source identifiers:
25231

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