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Expression of kinase interacting with stathmin (KIS, UHMK1) in human brain and lymphoblasts: Effects of schizophrenia and genotype.

Abstract:

Single nucleotide polymorphisms (SNPs) within the gene encoding the serine/threonine kinase KIS (Kinase Interacting with Stathmin, also known as UHMK1) have recently been associated with schizophrenia. As none of the disease associated SNPs are coding, they may confer susceptibility by altering some facet of KIS expression. Here we have characterised the cellular distribution of KIS in human brain using in situ hybridisation and immunohistochemistry, and quantified KIS protein and mRNA in two...

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Publication status:
Published

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Authors


Bristow, GC More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
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Journal:
Brain research
Volume:
1301
Pages:
197-206
Publication date:
2009-12-05
DOI:
EISSN:
1872-6240
ISSN:
0006-8993
URN:
uuid:67fa01c9-7b79-43ca-9b8b-85408105713f
Source identifiers:
97915
Local pid:
pubs:97915

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