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Journal article

Theobromine for the treatment of persistent cough: a randomised, multicentre, double-blind, placebo-controlled clinical trial

Abstract:

Background

To investigate the effect of BC1036 on health-related quality of life (QOL) in subjects with persistent cough. The secondary objective was to investigate the effect of BC1036 on subjective cough severity.

Methods

This was a randomised, multicentre, double-blind, placebo-controlled, parallel-group study in 289 subjects with persistent cough. Subjects received BC1036 or placebo twice daily for 14 days. The primary endpoint comprised cough-related QOL asse...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.21037/jtd.2017.06.18

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; Target Discovery Institute
Oxford college:
St Edmund Hall
Role:
Author
ORCID:
0000-0002-4288-5973
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Grant:
MRC-Asthma UK Centre
Publisher:
AME Publishing Company Publisher's website
Journal:
Journal of Thoracic Disease Journal website
Volume:
9
Issue:
7
Pages:
1864-1872
Publication date:
2017-07-31
Acceptance date:
2017-05-18
DOI:
ISSN:
2072-1439 and 2077-6624
Pubs id:
pubs:720371
URN:
uri:67cdd833-7b3c-4f73-93c8-c0c496744615
UUID:
uuid:67cdd833-7b3c-4f73-93c8-c0c496744615
Local pid:
pubs:720371

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