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Persistence of bactericidal antibodies following early infant vaccination with a serogroup B meningococcal vaccine and immunogenicity of a preschool booster dose.

Abstract:

BACKGROUND: The multicomponent serogroup B meningococcal (4CMenB) vaccine was recently licensed for use in Europe. There are currently no data on the persistence of bactericidal antibodies induced by use of this vaccine in infants. Our objective was to evaluate serogroup B-specific bactericidal antibodies in children aged 40-44 months previously vaccinated at 2, 4, 6 and 12 months of age. METHODS: Participants given 4 doses of 4CMenB as infants received a fifth dose of the vaccine at 40-44 m...

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Publication status:
Published

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Publisher copy:
10.1503/cmaj.130257

Authors


Journal:
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne More from this journal
Volume:
185
Issue:
15
Pages:
E715-E724
Publication date:
2013-10-01
DOI:
EISSN:
1488-2329
ISSN:
0820-3946
Language:
English
Keywords:
Pubs id:
pubs:431346
UUID:
uuid:67cd2538-5768-4870-8129-00cad5299dc4
Local pid:
pubs:431346
Source identifiers:
431346
Deposit date:
2013-11-17

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