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Stability of histone modifications across mammalian genomes: implications for 'epigenetic' marking.

Abstract:

The combination of chromatin immunoprecipitation (ChIP) with microarray analysis (ChIP-chip) or high-throughput sequencing (ChIP-seq and ChIP-SAGE) has provided maps of a wide variety of site-specific histone modifications across mammalian genomes in various cell types. Although distinct genomic regions and functional elements have been strongly associated with specific histone modifications, an overwhelming number of combinatorial patterns have also been observed across the genome. While pea...

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Publication status:
Published

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Publisher copy:
10.1002/jcb.22250
Journal:
Journal of cellular biochemistry More from this journal
Volume:
108
Issue:
1
Pages:
22-34
Publication date:
2009-09-01
DOI:
EISSN:
1097-4644
ISSN:
0730-2312
Language:
English
Keywords:
Pubs id:
pubs:202321
UUID:
uuid:67ccb391-f218-4d06-9436-5684f0782259
Local pid:
pubs:202321
Source identifiers:
202321
Deposit date:
2012-12-19

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