Journal article
The public health impact and cost-effectiveness of the R21/Matrix-M malaria vaccine: a mathematical modelling study
- Abstract:
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Background The R21/Matrix-M vaccine has demonstrated high efficacy against Plasmodium falciparum clinical malaria in children in sub-Saharan Africa. Using trial data, we aimed to estimate the public health impact and cost-effectiveness of vaccine introduction across sub-Saharan Africa.
Methods We fitted a semi-mechanistic model of the relationship between anti-circumsporozoite protein antibody titres and vaccine efficacy to data from 3 years of fol...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 1.5MB, Terms of use)
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- Publisher copy:
- 10.1016/S1473-3099(23)00816-2
Authors
Funding
Bibliographic Details
- Publisher:
- Elsevier
- Journal:
- Lancet Infectious Diseases More from this journal
- Volume:
- 24
- Issue:
- 5
- Pages:
- 465-475
- Place of publication:
- United States
- Publication date:
- 2024-02-08
- Acceptance date:
- 2023-12-18
- DOI:
- EISSN:
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1474-4457
- ISSN:
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1473-3099
- Pmid:
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38342107
Item Description
- Language:
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English
- Keywords:
- Pubs id:
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1630285
- Local pid:
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pubs:1630285
- Deposit date:
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2024-03-12
Terms of use
- Copyright holder:
- Schmit et al.
- Copyright date:
- 2024
- Rights statement:
- © 2024 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.
- Notes:
- For the purpose of open access, the author has applied a creative commons attribution licence to any author-accepted manuscript version arising from this submission.
- Licence:
- CC Attribution (CC BY)
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