Journal article icon

Journal article

Phantom pain is associated with preserved structure and function in the former hand area.

Abstract:

Phantom pain after arm amputation is widely believed to arise from maladaptive cortical reorganization, triggered by loss of sensory input. We instead propose that chronic phantom pain experience drives plasticity by maintaining local cortical representations and disrupting inter-regional connectivity. Here we show that, while loss of sensory input is generally characterized by structural and functional degeneration in the deprived sensorimotor cortex, the experience of persistent pain is ass...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1038/ncomms2571

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Publisher:
Springer Nature
Journal:
Nature Communications More from this journal
Volume:
4
Article number:
1570
Publication date:
2013-03-05
Acceptance date:
2013-02-01
DOI:
EISSN:
2041-1723
Language:
English
Keywords:
UUID:
uuid:67a8ea76-9525-46ca-a659-757a643dbb73
Local pid:
pubs:387725
Source identifiers:
387725
Deposit date:
2013-11-16

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP