- Abstract:
-
The time course of appearance of cells with DNA damage was studied in rats following transient severe forebrain ischemia. This DNA damage could be detected by in situ end-labeling on brain sections. The breaks in DNA appeared selectively by day 1 in the striatum and later in the CA1 region of the hippocampus. It was possible by double labeling to show that there was no DNA damage in astrocytes. The DNA breaks consisted of laddered DNA fragments indicative of an ordered apoptotic type of inter...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1038/jcbfm.1995.94
-
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- Journal:
- Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
- Volume:
- 15
- Issue:
- 5
- Pages:
- 728-737
- Publication date:
- 1995-09-05
- DOI:
- EISSN:
-
1559-7016
- ISSN:
-
0271-678X
- URN:
-
uuid:67a42bcc-474c-473d-92de-7d289d15d54d
- Source identifiers:
-
80181
- Local pid:
- pubs:80181
- Language:
- English
- Keywords:
- Copyright date:
- 1995
Journal article
Differences in DNA fragmentation following transient cerebral or decapitation ischemia in rats.
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