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Stereoselectivity in the double reductive alkylation of pyrroles: synthesis of cis-3,4-disubstituted pyrrolidines

Abstract:
The preparation and Birch reduction of a 1,3,4-tri-substituted pyrrole is described: the heterocycle is loaded with electron-withdrawing groups and undergoes a double reductive alkylation reaction to yield cis-3,4-disubstituted pyrrolidines.
Publication status:
Published

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Publisher copy:
10.1039/a809193e

Authors


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Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
Cousins, RPC More by this author
Journal:
CHEMICAL COMMUNICATIONS
Issue:
2
Pages:
141-142
Publication date:
1999-01-21
DOI:
EISSN:
1364-548X
ISSN:
1359-7345
URN:
uuid:679f9cc9-ef47-4564-8659-5e7bf9275362
Source identifiers:
36863
Local pid:
pubs:36863
Language:
English

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