Thesis icon

Thesis

Organoid models to characterise colonic stem cell plasticity

Abstract:

Cellular plasticity is the capability of cells to alter their phenotype in response to cues in the surrounding milieu, a vital property in several biological processes. The colon is a prime example of the importance of cellular plasticity in homeostasis as its epithelial lining is extremely dynamic, with cells constantly selecting between proliferation, differentiation, migration and apoptosis, depending on the needs of the tissue. While plasticity plays an important role in healthy tissue...

Expand abstract

Actions


Authors


More by this author
Division:
MSD
Department:
NDM
Sub department:
Oxford Ludwig Institute
Research group:
Lu
Oxford college:
University College
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Oxford Ludwig Institute
Research group:
Lu
Oxford college:
Magdalen College
Role:
Supervisor
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Research group:
Leedham
Role:
Supervisor
More from this funder
Name:
Clarendon Fund Scholarship
Programme:
NDM Prize Studentship
More from this funder
Name:
The Oxford-Radcliffe Scholarship
Programme:
NDM Prize Studentship
More from this funder
Name:
The Ludwig Institute for Cancer Research
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
DOI:

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP