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Genes for schizophrenia? Recent findings and their pathophysiological implications.

Abstract:

CONTEXT: Schizophrenia is highly heritable, but the genes have remained elusive. Identifying the genes is essential if the pathogenesis and pathophysiology of schizophrenia is finally to be understood, and to give the prospect of more effective treatment. STARTING POINT: H Stefansson and colleagues (Am J Hum Genet 2002; 71: 877-92) showed association of the neuregulin (NRG1) gene with schizophrenia. Other recent papers describe six additional susceptibility genes. Replications are already be...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Role:
Author
Journal:
Lancet
Volume:
361
Issue:
9355
Pages:
417-419
Publication date:
2003-02-05
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
URN:
uuid:67948a52-95f5-4d73-a20b-95ab7a471eea
Source identifiers:
98063
Local pid:
pubs:98063

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