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Journal article

Advanced non-alcoholic fatty liver disease and adipose tissue fibrosis in patients with Alstrom syndrome.

Abstract:

Alström syndrome (AS) is a recessive monogenic syndrome characterised by obesity, extreme insulin resistance and multi-organ fibrosis. Despite phenotypically being high risk of non-alcoholic fatty liver disease (NAFLD), there is a lack of data on the extent of fibrosis in the liver and its close links to adipose in patients with AS. Our aim is to characterise the hepatic and adipose phenotype in patients with AS.Observational cohort study with comprehensive assessment of metabolic liver pheno...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1111/liv.13163

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
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More from this funder
Grant:
104458/Z/14/Z
099909
WT098498
Science Lottery Grant More from this funder
Publisher:
Wiley Publisher's website
Journal:
Liver International Journal website
Volume:
36
Issue:
11
Pages:
1704–1712
Publication date:
2016-06-10
Acceptance date:
2016-04-23
DOI:
EISSN:
1478-3231
ISSN:
1478-3223
Source identifiers:
623444
Language:
English
Keywords:
Pubs id:
pubs:623444
UUID:
uuid:67860c37-c863-4b59-abfa-cdcc4af2027b
Local pid:
pubs:623444
Deposit date:
2016-07-05

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