Journal article
Predictors of exacerbation risk and response to budesonide in patients with chronic obstructive pulmonary disease: a post-hoc analysis of three randomised trials
- Abstract:
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The peripheral blood eosinophil count might help identify those patients with chronic obstructive pulmonary disease (COPD) who will experience fewer exacerbations when taking inhaled corticosteroids (ICS). Previous post-hoc analyses have proposed eosinophil cutoffs that are both arbitrary and limited in evaluating complex interactions of treatment response. We modelled eosinophil count as a continuous variable to determine the characteristics that determine both exacerbation risk and clinical...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
-
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(Accepted manuscript, pdf, 179.4KB)
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- Publisher copy:
- 10.1016/s2213-2600(18)30006-7
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Authors
Funding
AstraZeneca
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Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Lancet Respiratory Medicine Journal website
- Volume:
- 6
- Issue:
- 2
- Pages:
- 117-126
- Publication date:
- 2018-01-10
- Acceptance date:
- 2018-01-09
- DOI:
- EISSN:
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2213-2619
- ISSN:
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2213-2600
- Pmid:
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29331313
- Source identifiers:
-
821447
Item Description
- Language:
- English
- Pubs id:
-
pubs:821447
- UUID:
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uuid:674863ec-59a1-4902-bdbc-87a0425784a5
- Local pid:
- pubs:821447
- Deposit date:
- 2018-02-02
Terms of use
- Copyright holder:
- Elsevier Ltd
- Copyright date:
- 2018
- Notes:
- Copyright © 2018 Elsevier Ltd. This is the accepted manuscript version of the article. The final version is available online from Elsevier at: https://doi.org/10.1016/s2213-2600(18)30006-7
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