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Thermodynamic dissection of colicin interactions.

Abstract:

Bacteriocins are selective protein antibiotics that bind and kill specific bacterial species, the best studied of which are the colicins that target Escherichia coli. Colicins tend to parasitize cell envelope systems that are important for cell viability under nutrient-limited conditions or environmental stress. In this chapter, we review how in conjunction with other biophysical methods and structural information, isothermal titration calorimetry (ITC) has been used to investigate how colici...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
Journal:
Methods in enzymology
Volume:
488
Issue:
C
Pages:
123-145
Publication date:
2011-01-01
DOI:
EISSN:
1557-7988
ISSN:
0076-6879
Source identifiers:
310212

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