Journal article
A Flexible Approach for the Analysis of Rare Variants Allowing for a Mixture of Effects on Binary or Quantitative Traits
- Abstract:
-
Multiple rare variants either within or across genes have been hypothesised to collectively influence complex human traits. The increasing availability of high throughput sequencing technologies offers the opportunity to study the effect of rare variants on these traits. However, appropriate and computationally efficient analytical methods are required to account for collections of rare variants that display a combination of protective, deleterious and null effects on the trait. We have devel...
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Bibliographic Details
- Journal:
- PLoS Genetics
- Volume:
- 9
- Issue:
- 8
- Publication date:
- 2013-08-01
- DOI:
- EISSN:
-
1553-7404
- ISSN:
-
1553-7390
- Source identifiers:
-
432254
Item Description
- Language:
- English
- Pubs id:
-
pubs:432254
- UUID:
-
uuid:67459f9d-4850-4162-8d56-499db70a81e0
- Local pid:
- pubs:432254
- Deposit date:
- 2013-11-16
Terms of use
- Copyright date:
- 2013
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