Journal article icon

Journal article

Advances and challenges in understanding histone demethylase biology

Abstract:

Within the last decade we have witnessed significant progress in the field of chromatin methylation, ranging from the discovery that chromatin methylation is reversible, to the identification of two classes of oxidative chromatin demethylases. Multiple genetic and cellular studies emphasize the role of members of the amine oxidase and 2-oxoglutarate oxygenase enzyme families involved in methyl-lysine in physiology and disease. Advances in understanding of the underlying biochemistry have resu...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1016/j.cbpa.2016.06.021

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
Expand authors...
Cancer Research UK More from this funder
National Institutes for Health Research More from this funder
Rosetrees Trust More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Current Opinion in Chemical Biology Journal website
Volume:
33
Pages:
151-159
Publication date:
2016-08-01
Acceptance date:
2016-07-01
DOI:
EISSN:
1879-0402
ISSN:
1367-5931
Pmid:
27371875
Source identifiers:
634085
Language:
English
Keywords:
Pubs id:
pubs:634085
UUID:
uuid:6741ad62-cf29-4306-984a-329bac1601ae
Local pid:
pubs:634085
Deposit date:
2016-12-14

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP