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Chronic stress in elderly carers of dementia patients and antibody response to influenza vaccination.

Abstract:

BACKGROUND: There are many reports of psychological morbidity in spousal carers of patients with dementia. The consequences of this increased stress on the immune system are unclear. We investigated whether antibody responses to influenza vaccination differed between carers and a control group, and the relation of the antibody response to the hypothalamic-pituitary-adrenal (HPA) axis. METHODS: 50 spousal carers of dementia patients, median age 73 years (IQR 66-77), and 67 controls (68 years [...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
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Journal:
Lancet
Volume:
353
Issue:
9153
Pages:
627-631
Publication date:
1999-02-01
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
Source identifiers:
31432

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