Journal article
FOXM1 regulates proliferation, senescence and oxidative stress in keratinocytes and cancer cells
- Abstract:
-
Several transcription factors, including the master regulator of the epidermis, p63, are involved in controlling human keratinocyte proliferation and differentiation. Here, we report that in normal keratinocytes, the expression of FOXM1, a member of the Forkhead superfamily of transcription factors, is controlled by p63. We observe that, together with p63, FOXM1 strongly contributes to the maintenance of high proliferative potential in keratinocytes, whereas its expression decreases during di...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
Bibliographic Details
- Publisher:
- Impact Journals Publisher's website
- Journal:
- Aging Journal website
- Volume:
- 8
- Issue:
- 7
- Pages:
- 1384-1397
- Publication date:
- 2016-07-03
- Acceptance date:
- 2016-06-12
- DOI:
- EISSN:
-
1945-4589
- Pmid:
-
27385468
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:994545
- UUID:
-
uuid:673d5803-ed74-4e7e-8896-ca8431000147
- Local pid:
- pubs:994545
- Source identifiers:
-
994545
- Deposit date:
- 2019-04-29
Terms of use
- Copyright holder:
- Smirnov, A et al
- Copyright date:
- 2016
- Notes:
- © 2016 Smirnov, A et al. Article is licensed under a Creative Commons Attribution 3.0 License (CC BY 3.0).
- Licence:
- CC Attribution (CC BY)
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