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Thesis

Regulation and reproductive functions of membrane-bound vesicles secreted by the Drosophila male accessory gland

Abstract:

Membrane-bound vesicle secretion provides a novel intercellular communication mechanism, whose roles and regulation remain poorly characterised, particularly in vivo. I have identified two classes of lipid-containing, vesicle-like structures secreted into seminal fluid by epithelial cells of the Drosophila male accessory gland (AG). Exosomes, one class of membrane-bound vesicle formed inside late endosomal multivesicular bodies, are specifically secreted by secondary cell...

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Institution:
University of Oxford
Research group:
Wilson Groups
Oxford college:
Exeter College
Department:
Medical Sciences Division - Sherrington Building,Le Gros Clark Building
Role:
Author

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Role:
Supervisor
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Funding agency for:
Laura Corrigan
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:673d46a5-ba88-42d2-9361-51f04d61e01b
Local pid:
ora:9303

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