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A receptor's tale: An eon in the life of a trypanosome receptor

Abstract:

African trypanosomes have complex life cycles comprising at least ten developmental forms, variously adapted to different niches in their tsetse fly vector and their mammalian hosts. Unlike many other protozoan pathogens, they are always extracellular and have evolved intricate surface coats that allow them to obtain nutrients while also protecting them from the immune defenses of either insects or mammals. The acquisition of macromolecular nutrients requires receptors that function within th...

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Publication status:
Published
Peer review status:
Peer reviewed

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Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Oxford college:
Merton College
Role:
Author
ORCID:
0000-0002-2870-1955
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Biochemistry
Role:
Author
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Role:
Author
ORCID:
0000-0003-0919-3745
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Name:
Wellcome Trust
Grant:
101020/Z/13/Z
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Name:
Medical Research Council
Grant:
MR/P001424/1
MR/L008246/1
Publisher:
Public Library of Science
Journal:
PLoS Pathogens More from this journal
Volume:
13
Issue:
1
Article number:
e1006055
Publication date:
2017-01-26
Acceptance date:
2017-01-26
DOI:
EISSN:
1553-7374
ISSN:
1553-7366
Pmid:
28125726
Language:
English
Keywords:
Pubs id:
pubs:673484
UUID:
uuid:673c2e5e-3b8e-478d-9e7b-23ff3452f10b
Local pid:
pubs:673484
Source identifiers:
673484
Deposit date:
2019-02-27

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