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The memory function of noradrenergic activity in non-REM sleep

Abstract:

There is a long-standing assumption that low noradrenergic activity during sleep reflects mainly the low arousal during this brain state. Nevertheless, recent research has demonstrated that the locus coeruleus, which is the main source of cortical noradrenaline, displays discrete periods of intense firing during non-REM sleep, without any signs of awakening. This transient locus coeruleus activation during sleep seems to occur in response to preceding learning-related episodes. In the present...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1162/jocn.2011.21622

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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Volkswagen Stiftung More from this funder
Deutsche Forschungsgemeinschaft More from this funder
Publisher:
Massachusetts Institute of Technology Press Publisher's website
Journal:
Journal of Cognitive Neuroscience Journal website
Volume:
23
Issue:
9
Pages:
2582-2592
Publication date:
2011
DOI:
EISSN:
1530-8898
ISSN:
0898-929X
URN:
uuid:67338096-850e-4a30-8c90-40b1a6223959
Source identifiers:
577736
Local pid:
pubs:577736

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