LIPID HEADGROUP HYDRATION STUDIED BY H-2-NMR - A LINK BETWEEN SPECTROSCOPY AND THERMODYNAMICS

Journal article

The conformational and dynamic response of the phosphatidylcholine headgroup to hydration has been characterized by 2H-NMR measurements of selectively deuterated DOPC at positions α, β, and γ, and to complement the structural results from diffraction studies. Quadrupole splittings (ΔνQ) and spin-lattice relaxation rates (1/T1) were monitored over the range of water/lipid mole ratios from 4 to 100. Their hydration dependence reveals a concerted change in headgroup conformation together with an...

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Authors: Ulrich, A; Watts, A

• Publication status: Published
• Journal: BIOPHYSICAL CHEMISTRY
• Volume: 49
• Issue: 1
• Pages: 39-50
• Publication date: 1994-02-01
• DOI: 10.1016/0301-4622(93)E0080-O
• ISSN: 0301-4622
• Language: English
• Keywords: PHOSPHATIDYLCHOLINE BILAYERS; WATER ACTIVITY; SURFACE DYNAMICS; HEADGROUP CONFORMATION; LIPID HYDRATION; DEUTERIUM NMR; HYDRATION FORCE