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Role of inflammation and oxidative stress in endothelial progenitor cell function and mobilization: therapeutic implications for cardiovascular diseases.

Abstract:

Endothelial progenitor cells (EPCs) are mobilized from the bone marrow into the peripheral circulation, home to sites of injury, and incorporate into foci of neovascularization, thereby improving blood flow and tissue recovery. Patients with cardiovascular diseases, including coronary artery disease, heart failure, hypertension, and diabetes, have been shown to exhibit reduced number and functional capacity of EPCs. Considerable evidence indicates that EPCs constitute an important endogenous ...

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Journal:
Atherosclerosis More from this journal
Volume:
201
Issue:
2
Pages:
236-247
Publication date:
2008-12-01
DOI:
EISSN:
1879-1484
ISSN:
0021-9150
Language:
English
Keywords:
Pubs id:
pubs:223261
UUID:
uuid:672ece58-d7db-44ac-89ef-2df5532fc620
Local pid:
pubs:223261
Source identifiers:
223261
Deposit date:
2012-12-19

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