- Abstract:
-
The World Health Organization recommends the use of artemisinin-based combination therapies (ACTs) for the treatment of uncomplicated malaria. The two most widely adopted ACT regimens are artemether (AR)-lumefantrine (LR) (the combination is abbreviated AL) and amodiaquine (AQ)-artesunate (AS). Pharmacokinetic (PK) data informing the optimum dosing of these drug regimens is limited, especially in children. We evaluated PK parameters in Ugandan children aged 5 to 13 years with uncomplicated ma...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1128/aac.00679-09
-
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- Journal:
- Antimicrobial agents and chemotherapy
- Volume:
- 54
- Issue:
- 1
- Pages:
- 52-59
- Publication date:
- 2010-01-05
- DOI:
- EISSN:
-
1098-6596
- ISSN:
-
0066-4804
- URN:
-
uuid:6729d160-b577-4f42-8b41-b6281866e81c
- Source identifiers:
-
14233
- Local pid:
- pubs:14233
- Copyright date:
- 2010
Journal article
Pharmacokinetics of artemether-lumefantrine and artesunate-amodiaquine in children in Kampala, Uganda.
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