Selected contribution: Peripheral chemoreflex function in high-altitude natives and patients with chronic mountain sickness.

Journal article

Peripheral chemoreflex function was studied in high-altitude (HA) natives at HA, in patients with chronic mountain sickness (CMS) at HA, and in sea-level (SL) natives at SL. Results were as follows. 1) Acute ventilatory responses to hypoxia (AHVR) in the HA and CMS groups were approximately one-third of those of the SL group. 2) In CMS patients, some indexes of AHVR were modestly, but significantly, lower than in healthy HA natives. 3) Prior oxygenation increased AHVR in all subject groups. 4...

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Authors: Léon-Velarde, F; Gamboa, A; Rivera-Ch, M; Palacios, J; Robbins, P

• Publication status: Published
• Journal: Journal of applied physiology (Bethesda, Md. : 1985)
• Volume: 94
• Issue: 3
• Pages: 1269-1278
• Publication date: 2003-03-01
• DOI: 10.1152/japplphysiol.00858.2002
• EISSN: 1522-1601
• ISSN: 8750-7587
• Language: English
• Keywords: Carotid Body; Reflex; Altitude; Female; Hematocrit; Hypercapnia; Chronic Disease; Male; Hyperoxia; Adaptation, Physiological; Altitude Sickness; Somatostatin; Anoxia; Humans; Chemoreceptor Cells; Dopamine; Adult