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Low tolerability of carbamazepine in psychiatric patients may restrict its clinical usefulness.

Abstract:

There are reports of prophylactic efficacy of carbamazepine (CBZ) in manic depres sives when compared with placebo and chlorpromazine. Following a successful open pilot study by one of the authors, an attempt was made to compare carbamazepine and lithium carbonate in a double-blind, crossover trial, each patient being assigned to take each drug for 9 months in random order. However, of the first 14 patients to take carbamazepine four were withdrawn because of drug rashes and another two becau...

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Publisher copy:
10.1177/026988118800200101

Authors


Elphick, M More by this author
Journal:
Journal of psychopharmacology (Oxford, England)
Volume:
2
Issue:
1
Pages:
1-4
Publication date:
1988-01-05
DOI:
EISSN:
1461-7285
ISSN:
0269-8811
URN:
uuid:67138461-e51a-4394-b426-9052cd2cdbcb
Source identifiers:
186072
Local pid:
pubs:186072
Language:
English

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