- Abstract:
-
The rationale for anti-tumour necrosis factor-alpha (anti-TNFalpha) therapy in rheumatoid arthritis (RA) is based on experiments on cultures of human rheumatoidjoint tissue, supported by experiments in animal models, all of which demonstrated that anti-TNFalpha antibody had profound effects on the disease activity. Clinical trials have substantiated this concept, and we have used the serum samples from the clinical trials, as well as biopsies to study the changes occurring during anti-TNFalph...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1159/000237393
-
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- Journal:
- International archives of allergy and immunology
- Volume:
- 111
- Issue:
- 4
- Pages:
- 362-365
- Publication date:
- 1996-12-05
- DOI:
- EISSN:
-
1423-0097
- ISSN:
-
1018-2438
- URN:
-
uuid:66fae182-1ebf-452a-9dbf-3659764d3e24
- Source identifiers:
-
481618
- Local pid:
- pubs:481618
- Language:
- English
- Keywords:
- Copyright date:
- 1996
Journal article
What is the mechanism of action of anti-tumour necrosis factor-alpha antibody in rheumatoid arthritis?
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