Journal article
The 3-dimensional structure of a hepatitis C virus p7 ion channel by electron microscopy.
- Abstract:
-
Infection with the hepatitis C virus (HCV) has a huge impact on global health putting more than 170 million people at risk of developing severe liver disease. The HCV encoded p7 ion channel is essential for the production of infectious viruses. Despite a growing body of functional data, little is known about the 3-dimensional (3D) structure of the channel. Here, we present the 3D structure of a full-length viroporin, the detergent-solubilized hexameric 42 kDa form of the HCV p7 ion channel, a...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
Oxford Glycobiology Institute Endowment
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Bibliographic Details
- Publisher:
- National Academy of Sciences Publisher's website
- Journal:
- Proceedings of the National Academy of Sciences Journal website
- Volume:
- 106
- Issue:
- 31
- Pages:
- 12712-12716
- Publication date:
- 2009-08-04
- DOI:
- EISSN:
-
1091-6490
- ISSN:
-
0027-8424
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:100077
- UUID:
-
uuid:66e9181a-bc5c-4a01-ab2d-9ecadc7be3ed
- Local pid:
- pubs:100077
- Source identifiers:
-
100077
- Deposit date:
- 2012-12-19
Terms of use
- Copyright holder:
- Luik et al
- Copyright date:
- 2009
- Notes:
- Author(s) retain copyright; published by the National Academy of Sciences under license. The final version is available online from the National Academy of Sciences at: [10.1073/pnas.0905966106].
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