Targeting tyrosine-kinases in ovarian cancer.

Journal article

INTRODUCTION: Epithelial ovarian cancer (EOC) is the leading cause of gynaecologic cancer death. Although in some cases initial treatment is effective, most of the women diagnosed with EOC will probably need medical treatment for their disease. There is a critical need to develop effective new strategies for the management of patients with advanced or recurrent EOC, and targeted therapy with tyrosine kinase inhibitors (TKIs) has continued to be an area of active research and development in th...

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Authors: Morotti, M; Becker, C; Menada, M; Ferrero, S

• Publication status: Published
• Journal: Expert opinion on investigational drugs
• Volume: 22
• Issue: 10
• Pages: 1265-1279
• Publication date: 2013-10-01
• DOI: 10.1517/13543784.2013.816282
• EISSN: 1744-7658
• ISSN: 1354-3784
• Language: English
• Keywords: Protein-Tyrosine Kinases; Biological Markers; Humans; Female; Protein Kinase Inhibitors; Antineoplastic Agents; Treatment Outcome; Clinical Trials as Topic; Ovarian Neoplasms