Journal article
Genome-wide association study meta-analysis of neurofilament light (NfL) levels in blood reveals novel loci related to neurodegeneration
- Abstract:
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Neurofilament light chain (NfL) levels in circulation have been established as a sensitive biomarker of neuro-axonal damage across a range of neurodegenerative disorders. Elucidation of the genetic architecture of blood NfL levels could provide new insights into molecular mechanisms underlying neurodegenerative disorders. In this meta-analysis of genome-wide association studies (GWAS) of blood NfL levels from eleven cohorts of European ancestry, we identify two genome-wide significant loci at...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Publisher copy:
- 10.1038/s42003-024-06804-3
Authors
Bibliographic Details
- Publisher:
- Nature Research
- Journal:
- Communications Biology More from this journal
- Volume:
- 7
- Issue:
- 1
- Article number:
- 1103
- Publication date:
- 2024-09-09
- Acceptance date:
- 2024-08-29
- DOI:
- EISSN:
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2399-3642
Item Description
- Language:
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English
- Source identifiers:
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2250487
- Deposit date:
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2024-09-10
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