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Journal article

Establishing COVID-19 trials at scale and pace: experience from the RECOVERY trial

Abstract:

The Randomised Evaluation of COVID-19 Therapy (RECOVERY) Trial was set up in March 2020 to evaluate treatments for people hospitalised with COVID-19. To maximise recruitment it was designed to fit into routine clinical care throughout the UK, and as a result it has enrolled more patients than any other COVID-19 treatment trial. RECOVERY has shown four drugs to be life-saving – dexamethasone, tocilizumab, baricitinib and casirivimab-imdevimab – and a further six have been shown to be of little...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.jbior.2022.100901

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Role:
Author
ORCID:
0000-0002-4100-2163
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
ORCID:
0000-0002-9822-1586
National Institute for Health Research More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Advances in Biological Regulation
Article number:
100901
Publication date:
2022-07-19
Acceptance date:
2022-07-14
DOI:
EISSN:
2212-4934
ISSN:
2212-4926
Pmid:
35915043
Language:
English
Keywords:
Pubs id:
1273214
Local pid:
pubs:1273214
Deposit date:
2022-08-16

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