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Developmental changes in the functional characteristics and expression of voltage-gated K+ channel currents in rat aortic myocytes.

Abstract:

OBJECTIVE: Active control of the arterial diameter by vascular smooth muscle is one of the principle mechanisms by which vessels adapt to a significant rise in blood pressure after birth. Although voltage-gated K+ (Kv) channels play an important role in the regulation of excitation-contraction coupling in arteries, very little is known about postnatal modification of Kv channels. We therefore investigated changes in the functional characteristics and expression of Kv channels in rat aortic m...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Pharmacology
Role:
Author
Publisher:
Elsevier
Journal:
Cardiovascular research
Volume:
54
Issue:
1
Pages:
152-161
Publication date:
2002-04-05
DOI:
EISSN:
1755-3245
ISSN:
0008-6363
URN:
uuid:66b8faa6-666f-4e9a-9c1e-a824533e461d
Source identifiers:
386842
Local pid:
pubs:386842

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