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Immunogenicity and immune memory of a nonadjuvanted quadrivalent meningococcal glycoconjugate vaccine in infants.

Abstract:

BACKGROUND: The highest rate of invasive meningococcal disease is among children under 2 years of age. There is currently no licensed quadrivalent (serogroups A, C, W-135, and Y) meningococcal glycoconjugate vaccine approved for infants. We evaluated the immunogenicity and reactogenicity of a novel quadrivalent nonadjuvanted meningococcal glycoconjugate vaccine (MenACWY-CRM) in healthy infants. METHODS: One hundred eighty infants (90 in Canada and 90 in the United Kingdom) received 2 doses o...

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Publication status:
Published

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Journal:
The Pediatric infectious disease journal
Volume:
28
Issue:
3
Pages:
186-193
Publication date:
2009-03-05
DOI:
EISSN:
1532-0987
ISSN:
0891-3668
URN:
uuid:66b2e7df-41b4-4e55-ab78-dc367f894de1
Source identifiers:
119263
Local pid:
pubs:119263

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