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Imaging of intracellular sodium with shift reagent aided (23)Na CSI in isolated rat hearts.

Abstract:

23Na chemical shift imaging (CSI) in conjunction with shift reagents was used to obtain images of intracellular (Na(i)) and extracellular sodium (Na(e)) in isolated rat hearts. It was demonstrated that the increase of Na(i) concentration in ischemic myocardium can be detected with this technique. 3D acquisition-weighted (23)Na CSI datasets with a nominal spatial resolution of 1.7 x 1.7 x 2.9 mm were acquired in 30 min in normoxic hearts and in globally or locally ischemic hearts. The shift re...

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Publication status:
Published

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Publisher copy:
10.1002/mrm.10205

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
Journal:
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine More from this journal
Volume:
48
Issue:
1
Pages:
89-96
Publication date:
2002-07-01
DOI:
EISSN:
1522-2594
ISSN:
0740-3194
Language:
English
Keywords:
Pubs id:
pubs:124818
UUID:
uuid:66a49c8e-f082-41ff-b5a3-5021a74edac9
Local pid:
pubs:124818
Source identifiers:
124818
Deposit date:
2012-12-19

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