- Abstract:
-
BACKGROUND: Severe malaria is characterized by microvascular obstruction, endothelial dysfunction, and reduced levels of L-arginine and nitric oxide (NO). L-Arginine infusion improves endothelial function in moderately severe malaria. Neither the longitudinal course of endothelial dysfunction nor factors associated with recovery have been characterized in severe malaria. METHODS: Endothelial function was measured longitudinally in adults with severe malaria (n = 49) or moderately severe malar...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1086/590209
-
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- Journal:
- The Journal of infectious diseases
- Volume:
- 198
- Issue:
- 4
- Pages:
- 602-608
- Publication date:
- 2008-08-05
- DOI:
- EISSN:
-
1537-6613
- ISSN:
-
0022-1899
- URN:
-
uuid:6688329a-9ba2-4ddc-83cf-5422e1d38020
- Source identifiers:
-
61499
- Local pid:
- pubs:61499
- Language:
- English
- Keywords:
- Copyright date:
- 2008
Journal article
Recovery of endothelial function in severe falciparum malaria: relationship with improvement in plasma L-arginine and blood lactate concentrations.
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