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Journal article

Highly avid, oligoclonal, early-differentiated antigen-specific CD8+ T cells in chronic HIV-2 infection.

Abstract:

HIV-1-specific CD8(+) T cells are present in most HIV-1-infected people and play an important role in controlling viral replication, but the characteristics of an effective HIV-specific T-cell response are largely unknown. The majority of HIV-2-infected people behave as long-term non-progressors while those who progress to AIDS do so in a manner indistinguishable from HIV-1. A detailed study of HIV-2 infection may identify protective immune responses. Robust gag p26-specific T-cell responses ...

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Publication status:
Published

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Publisher copy:
10.1002/eji.200940295

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Journal:
European journal of immunology
Volume:
40
Issue:
7
Pages:
1963-1972
Publication date:
2010-07-05
DOI:
EISSN:
1521-4141
ISSN:
0014-2980
URN:
uuid:667a7276-2b60-42b9-ad2b-9412a3787764
Source identifiers:
95277
Local pid:
pubs:95277

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