- Abstract:
-
The FOXP1 (forkhead box P1) transcription factor is a marker of poor prognosis in diffuse large B-cell lymphoma (DLBCL). Here microarray analysis of FOXP1-silenced DLBCL cell lines identified differential regulation of immune response signatures and major histocompatibility complex class II (MHC II) genes as some of the most significant differences between germinal center B-cell (GCB)-like DLBCL with full-length FOXP1 protein expression versus activated B-cell (ABC)-like DLBCL expressing pred...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 1.9MB)
-
- Publisher copy:
- 10.1038/leu.2015.299
-
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- Publisher:
- Nature Publishing Group Publisher's website
- Journal:
- Leukemia Journal website
- Volume:
- 30
- Issue:
- 3
- Pages:
- 605-616
- Publication date:
- 2015-11-17
- Acceptance date:
- 2015-10-13
- DOI:
- EISSN:
-
1476-5551
- ISSN:
-
0887-6924
- URN:
-
uuid:6675a9b8-c998-474a-8a10-74e2a31c2adc
- Source identifiers:
-
587283
- Local pid:
- pubs:587283
- Paper number:
- 3
- Language:
- English
- Keywords:
- Copyright holder:
- Macmillan Publishers Limited
- Copyright date:
- 2015
- Notes:
-
This work is licensed under a Creative Commons Attribution 4.0
International License. The images or other third party material in this
article are included in the article’s Creative Commons license, unless indicated
otherwise in the credit line; if the material is not included under the Creative Commons
license, users will need to obtain permission from the license holder to reproduce the
material. To view a copy of this license, visit http://creativecommons.org/licenses/
by/4.0/
Journal article
FOXP1 suppresses immune response signatures and MHC class II expression in activated B-cell-like diffuse large B-cell lymphomas
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