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Journal article

Large dense-core vesicle exocytosis in pancreatic beta-cells monitored by capacitance measurements.

Abstract:
This article discusses the currently used methodologies for monitoring exocytosis as changes in cell capacitance. Details are given on composition of solutions, experimental protocols, and how the observed responses can be interpreted physiologically. The concepts are illustrated by examples from our own work on insulin-releasing pancreatic beta-cells. Finally, we consider the feasibility of applying capacitance measurements to endocrine cells in intact pancreatic islets, where the cells are electrically coupled to each other.
Publication status:
Published

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Publisher copy:
10.1016/j.ymeth.2004.01.003

Authors


Eliasson, L More by this author
Galvanovskis, J More by this author
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Journal:
Methods (San Diego, Calif.)
Volume:
33
Issue:
4
Pages:
302-311
Publication date:
2004-08-05
DOI:
EISSN:
1095-9130
ISSN:
1046-2023
URN:
uuid:66330cf1-f7f4-45e7-b5d4-ca606047b878
Source identifiers:
22647
Local pid:
pubs:22647

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