Journal article
Extensive characterization of NF-κB binding uncovers non-canonical motifs and advances the interpretation of genetic functional traits.
- Abstract:
-
BACKGROUND: Genetic studies have provided ample evidence of the influence of non-coding DNA polymorphisms on trait variance, particularly those occurring within transcription factor binding sites. Protein binding microarrays and other platforms that can map these sites with great precision have enhanced our understanding of how a single nucleotide polymorphism can alter binding potential within an in vitro setting, allowing for greater predictive capability of its effect on a transcription fa...
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- Publication status:
- Published
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- Publisher copy:
- 10.1186/gb-2011-12-7-r70
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Bibliographic Details
- Journal:
- Genome biology
- Volume:
- 12
- Issue:
- 7
- Pages:
- R70
- Publication date:
- 2011-01-01
- DOI:
- EISSN:
-
1465-6914
- ISSN:
-
1465-6906
- Source identifiers:
-
167557
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:167557
- UUID:
-
uuid:6624c4e6-7b87-4f2a-8a7a-fbb8501fc1fb
- Local pid:
- pubs:167557
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2011
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