Functionally specific reorganization in human premotor cortex.

Journal article

After unilateral stroke, the dorsal premotor cortex (PMd) in the intact hemisphere is often more active during movement of an affected limb. Whether this contributes to motor recovery is unclear. Functional magnetic resonance imaging (fMRI) was used to investigate short-term reorganization in right PMd after transcranial magnetic stimulation (TMS) disrupted the dominant left PMd, which is specialized for action selection. Even when 1 Hz left PMd TMS had no effect on behavior, there was a comp...

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Authors: O'Shea, J; Johansen-Berg, H; Trief, D; Göbel, S; Rushworth, M

• Publication status: Published
• Journal: Neuron
• Volume: 54
• Issue: 3
• Pages: 479-490
• Publication date: 2007-05-01
• DOI: 10.1016/j.neuron.2007.04.021
• EISSN: 1097-4199
• ISSN: 0896-6273
• Language: English
• Keywords: Functional Laterality; Magnetic Resonance Imaging; Female; Adult; Neuronal Plasticity; Psychomotor Performance; Image Processing, Computer-Assisted; Evoked Potentials, Motor; Recovery of Function; Nerve Net; Humans; Reaction Time; Male; Brain Mapping; Oxygen; Motor Cortex; Transcranial Magnetic Stimulation; Stroke