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Journal article

The role of transposable elements in the regulation of IFN-lambda1 gene expression.

Abstract:

IFNs lambda1, lambda2, and lambda3, or type III IFNs, are recently identified cytokines distantly related to type I IFNs. Despite an early evolutionary divergence, the 2 types of IFNs display similar antiviral activities, and both are produced primarily in dendritic cells. Although virus induction of the type I IFN-beta gene had served as a paradigm of gene regulation, relatively little is known about the regulation of IFN-lambda gene expression. Studies of virus induction of IFN-lambda1 iden...

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Publication status:
Published

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Publisher copy:
10.1073/pnas.0904477106

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Journal:
Proceedings of the National Academy of Sciences of the United States of America
Volume:
106
Issue:
28
Pages:
11564-11569
Publication date:
2009-07-01
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
Source identifiers:
227194
Language:
English
Keywords:
Pubs id:
pubs:227194
UUID:
uuid:65ea4f9e-19fb-4877-8972-df6e9a14899c
Local pid:
pubs:227194
Deposit date:
2012-12-19

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